ollows the journey of a time traveler from the post-apocalyptic future who appears in present day on a mission to locate and eradicate the source of a deadly plague that will eventually decimate the human race.
27 years after a virus wipes out most of humanity, scientists send a man back to 2015 to stop the plague from ever happening. Cole's only lead is a virologist, who knows the dangerous source of the outbreak.
The trail of a mysterious organization called the “Army of the 12 Monkeys” leads Cole to a mental institution in 2015, where a patient holds the key to the plague that destroys the world. Meanwhile, despite warnings that her involvement may disrupt the course of history, Dr. Railly risks her life to help him.