Dorothy's daughter, Kate, comes to Miami with an announcement. She's engaged to a podiatrist named Dennis. Dorothy is thrilled but her happiness quickly turns to anger when she realizes that ex-husband, Stan, is going to be invited. After 38 years of marriage, Stan had left Dorothy for a woman half her age. Dorothy threatens to make a scene at the reception which places Rose and Blanche in the role of peacemaker.
Having not dated since her husband died, Rose reluctantly agrees to go on a blind date. This date turns into a serious relationship when she is invited on a cruise which would involve sharing a stateroom.
Blanche's sister, Virginia, comes to Miami for a visit and Blanche is convinced she's after something. Later, while out to dinner, she learns just what Virginia is after, Blanche's kidney. Meanwhile, Rose and Dorothy babysit for an infant.
A doctor Dorothy dates makes a pass at Blanche. But when Blanche tells Dorothy about it, Dorothy doesn't believe her. Dorothy accuses her of being a slut and when Blanche can't take no more she orders Dorothy to move out.
In a bowling competition, it's Dorothy and Blanche verses Rose and Sophia. If Sophia and Rose win, Dorothy will allow Sophia to go back to Sicily for a visit with an old beau and if Dorothy and Blanche win Sophia will give her a pair of antique earrings.
After a Madonna concert, the girls arrive home to discover their house has been broken into. This leads the girls to seek out means to protect themselves, including a security system, guard dog and mace. Meanwhile, Rose becomes so paranoid that the robbers will come back she goes so far as to purchase a gun.
Dorothy's ex-husband, Stan shows up to settle a piece of land they bought on their honeymoon. This leads to Dorothy and Stan spending the night together. Meanwhile, Rose and Blanche plan a vacation that Sophia is not invited on.
Dorothy latest boyfriend Glen gives her a shock when he tells her that he's married. She surprises herself when she finds herself sneaking around to be with him. Meanwhile, Blanche unloads her old car on Rose in order to buy a new one.
Rose is apprehensive about a visit from her daughter and granddaughter, since their reason for coming is to settle Rose's late-husband's will. Meanwhile, Blanche gets caught up in the tabloids of a society murder.
Blanche's psychology professor sexually harasses her when she goes to him for help on a difficult test. Blanche's professor makes her an harassing deal: If she has sex with him, he'll give her an ""A"" for the exam. Meanwhile, Dorothy, Rose and Sophia each try to get a hold of tickets for a sold out Frank Sinatra concert.
When Rose loses her job at the grief center, she begins searching for other sources of work. Meanwhile, Blanche tries to lose a few pounds and Dorothy is excited when a man she once had a crush on, contacts her and asks her out.
Blanche's father, Big Daddy, comes to Miami for a visit, with an announcement, he's sold the family plantation and is setting out to become a country singer. Meanwhile, Sophia places a ""curse"" on a neighbor who refuses to remove his tree that fell over onto the lanai during a storm.