harlie Berns (William H. Macy) is a veteran Hollywood movie producer who has given up on his career and life. That is until his idealistic screenwriter nephew (Jason Ritter) comes bearing the script of a lifetime and Charlie decides to give his career one final shot. The only thing standing in his way is Diedre Hearn (Meg Ryan), a sharp-witted studio executive brought in to keep Charlie in line.

Overview from themoviedb.org